Tetrahydrofuran → 3-[2-(2-Ethylbenzoimidazol-1-yl)-9-methyl-6-morpholin-4-yl-9H-purin-8-yl]-3-hydroxy-azetidine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:41]([CH3:42])([CH3:43])([CH3:44])[O:45][C:46](=[O:47])[N:48]1[CH2:49][C:50](=[O:52])[CH2:51]1.[CH2:1]([CH3:2])[c:3]1[n:4][c:5]2[c:6]([n:7]1-[c:8]1[n:9][c:10]([N:18]3[CH2:19][CH2:20][O:21][CH2:22][CH2:23]3)[c:11]3[n:12][cH:13][n:14]([CH3:17])[c:15]3[n:16]1)[cH:24][cH:25][cH:26][cH:27]2.[CH2:53]1[O:54][CH2:55][CH2:56][CH2:57]1.[CH3:28][N:29]([CH3:30])[CH2:31][CH2:32][N:33]([CH3:34])[CH3:35].[CH3:36][CH2:37][CH2:38][CH2:39][Li:40]>>[CH2:1]([CH3:2])[c:3]1[n:4][c:5]2[c:6]([n:7]1-[c:8]1[n:9][c:10]([N:18]3[CH2:19][CH2:20][O:21][CH2:22][CH2:23]3)[c:11]3[n:12][c:13]([C:50]4([OH:52])[CH2:49][N:48]([C:46]([O:45][C:41]([CH3:42])([CH3:43])[CH3:44])=[O:47])[CH2:51]4)[n:14]([CH3:17])[c:15]3[n:16]1)[cH:24][cH:25][cH:26][cH:27]2Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-57530a068fd045df8a01b3e885c1e386
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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