Methanol → tert-butyl 6-(8-(benzo[d]thiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl)-3-(3-hydroxypropyl)picolinate
Reaction equation
[BH4-:40].[CH2:42]1[O:43][CH2:44][CH2:45][CH2:46]1.[CH3:47][OH:48].[Na+:41].[s:1]1[c:2]([NH:10][C:11](=[O:12])[c:13]2[cH:14][cH:15][cH:16][c:17]3[c:22]2[CH2:21][N:20]([c:23]2[cH:24][cH:25][c:26]([CH2:36][CH2:37][CH:38]=[O:39])[c:27]([C:29](=[O:30])[O:31][C:32]([CH3:33])([CH3:34])[CH3:35])[n:28]2)[CH2:19][CH2:18]3)[n:3][c:4]2[c:5]1[cH:6][cH:7][cH:8][cH:9]2>>[s:1]1[c:2]([NH:10][C:11](=[O:12])[c:13]2[cH:14][cH:15][cH:16][c:17]3[c:22]2[CH2:21][N:20]([c:23]2[cH:24][cH:25][c:26]([CH2:36][CH2:37][CH2:38][OH:39])[c:27]([C:29](=[O:30])[O:31][C:32]([CH3:33])([CH3:34])[CH3:35])[n:28]2)[CH2:19][CH2:18]3)[n:3][c:4]2[c:5]1[cH:6][cH:7][cH:8][cH:9]2Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-fefd3ce1cb0d47c184be92961849ffb8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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