Dichloromethane → Methyl 3-{3'-[(tert-butoxycarbonylmethylamino)methyl]biphenyl-4-yl}-2-ethoxypropionate

HRID 1117894Notes

Reaction equation

HRID 1117894 reaction equation
[C:1]([O:2][C:3]([CH3:4])([CH3:5])[CH3:6])([O:7][C:8]([CH3:9])([CH3:10])[CH3:11])=[O:12].[CH2:13]([CH3:14])[O:15][CH:16]([C:17](=[O:18])[O:19][CH3:20])[CH2:21][c:22]1[cH:23][cH:24][c:25](-[c:28]2[cH:29][c:30]([CH2:34][NH:35][CH3:36])[cH:31][cH:32][cH:33]2)[cH:26][cH:27]1.[CH3:37][CH2:38][N:39]([CH2:40][CH3:41])[CH2:42][CH3:43].[Cl:44][CH2:45][Cl:46]>>[C:1]([O:7][C:8]([CH3:9])([CH3:10])[CH3:11])(=[O:12])[CH2:36][NH:35][CH2:34][c:30]1[cH:29][c:28](-[c:25]2[cH:24][cH:23][c:22]([CH2:21][CH:16]([O:15][CH2:13][CH3:14])[C:17](=[O:18])[O:19][CH3:20])[cH:27][cH:26]2)[cH:33][cH:32][cH:31]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 10219638Carbonic acid, bis(1,1-dimethylethyl) esterHCID 68851535Methyl 2-ethoxy-3-(3'-methylaminomethylbiphenyl-4-yl)propionate

Product 1

HCID 68850052Methyl 3-{3'-[(tert-butoxycarbonylmethylamino)methyl]biphenyl-4-yl}-2-ethoxypropionate

Sources & evidence

ORD record
ord-308b33717f8f4862a95037bbf30bedb3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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