Toluene → Tert-butyl 4-(4-chloro-2-methylphenyl)piperazine-1-carboxylate
Reaction equation
[Br:1][c:2]1[c:3]([CH3:9])[cH:4][c:5]([Cl:8])[cH:6][cH:7]1.[C:23]([P:24]([C:25]([CH3:26])([CH3:27])[CH3:28])[C:29]([CH3:30])([CH3:31])[CH3:32])([CH3:33])([CH3:34])[CH3:35].[C:36](=[O:37])([O-:38])[O-:39].[CH3:42][c:43]1[cH:44][cH:45][cH:46][cH:47][cH:48]1.[Cs+:40].[Cs+:41].[N:10]1([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:11][CH2:12][NH:13][CH2:14][CH2:15]1.[O:51]=[C:52]([CH:53]=[CH:54][c:55]1[cH:56][cH:57][cH:58][cH:59][cH:60]1)[CH:61]=[CH:62][c:63]1[cH:64][cH:65][cH:66][cH:67][cH:68]1.[O:69]=[C:70]([CH:71]=[CH:72][c:73]1[cH:74][cH:75][cH:76][cH:77][cH:78]1)[CH:79]=[CH:80][c:81]1[cH:82][cH:83][cH:84][cH:85][cH:86]1.[O:87]=[C:88]([CH:89]=[CH:90][c:91]1[cH:92][cH:93][cH:94][cH:95][cH:96]1)[CH:97]=[CH:98][c:99]1[cH:100][cH:101][cH:102][cH:103][cH:104]1.[Pd:49].[Pd:50]>>[c:2]1([N:13]2[CH2:12][CH2:11][N:10]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:15][CH2:14]2)[c:3]([CH3:9])[cH:4][c:5]([Cl:8])[cH:6][cH:7]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-12b1ca5147964c56bb230f8ce7a0a1d3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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