Dichloromethane → (2-(2-ethyl-1H-benzo[d]imidazol-1-yl)-9-methyl-6-morpholino-9H-purin-8-yl)(piperidin-4-yl)methanol
Reaction equation
[CH2:1]([CH3:2])[c:3]1[n:4][c:5]2[c:6]([n:7]1-[c:8]1[n:9][c:10]([N:33]3[CH2:34][CH2:35][O:36][CH2:37][CH2:38]3)[c:11]3[n:12][c:13]([CH:18]([CH:19]4[CH2:20][CH2:21][N:22]([C:25]([O:26][C:27]([CH3:28])([CH3:29])[CH3:30])=[O:31])[CH2:23][CH2:24]4)[OH:32])[n:14]([CH3:17])[c:15]3[n:16]1)[cH:39][cH:40][cH:41][cH:42]2.[CH2:43]([Cl:44])[Cl:45].[OH:46][C:47]([C:48]([F:49])([F:50])[F:51])=[O:52]>>[CH2:1]([CH3:2])[c:3]1[n:4][c:5]2[c:6]([n:7]1-[c:8]1[n:9][c:10]([N:33]3[CH2:34][CH2:35][O:36][CH2:37][CH2:38]3)[c:11]3[n:12][c:13]([CH:18]([CH:19]4[CH2:20][CH2:21][NH:22][CH2:23][CH2:24]4)[OH:32])[n:14]([CH3:17])[c:15]3[n:16]1)[cH:39][cH:40][cH:41][cH:42]2Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-9a87a31f59634d5a9df51ee595e47c75
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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