Chloride → (5-Bromo-2-fluoro-4-methoxy-phenyl)-(3-fluoro-phenyl)-methanone

HRID 111817Notes

Reaction equation

HRID 111817 reaction equation
[Al+3:2].[Br:15][c:16]1[c:17]([O:23][CH3:24])[cH:18][c:19]([F:22])[cH:20][cH:21]1.[Cl-:1].[Cl-:3].[Cl-:4].[Cl:26][CH2:27][Cl:28].[F:5][c:6]1[cH:7][c:8]([C:9](=[O:10])[Cl:11])[cH:12][cH:13][cH:14]1.[OH2:25]>>[F:5][c:6]1[cH:7][c:8]([C:9](=[O:10])[c:20]2[c:19]([F:22])[cH:18][c:17]([O:23][CH3:24])[c:16]([Br:15])[cH:21]2)[cH:12][cH:13][cH:14]1

Participants

7

Reactant 6

HCID 312Chloride3×HCID 962WaterHCID 6344DichloromethaneHCID 743763-Fluorobenzoyl chlorideHCID 104727Aluminum CationHCID 70180432-Bromo-5-fluoroanisole

Product 1

HCID 22260993(5-Bromo-2-fluoro-4-methoxy-phenyl)-(3-fluoro-phenyl)-methanone

Sources & evidence

ORD record
ord-c8186b7b2b1447bfade75589a5ed9467
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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