Ethanol → tert-butyl N-[4-[1-bromo-3-(trifluoromethyl)-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-4-oxo-1-(2,4,5-trifluorophenyl)butan-2-yl]carbamate
Reaction equation
[Br:36][N:37]1[C:38](=[O:39])[CH2:40][CH2:41][C:42]1=[O:43].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH:8]([CH2:9][C:10]([N:11]1[CH2:12][c:13]2[n:14]([c:17]([C:20]([F:21])([F:22])[F:23])[n:18][cH:19]2)[CH2:15][CH2:16]1)=[O:24])[CH2:25][c:26]1[c:27]([F:34])[cH:28][c:29]([F:33])[c:30]([F:32])[cH:31]1)=[O:35].[C:44](=[O:45])([O-:46])[O-:47].[CH3:50][C:51]([O:52][C:53]([O:54][C:55]([O:56][C:57]([CH3:58])([CH3:59])[CH3:60])=[O:61])=[O:62])([CH3:63])[CH3:64].[CH3:65][CH2:66][OH:67].[K+:48].[K+:49]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH:8]([CH2:9][C:10]([N:11]1[CH2:12][c:13]2[n:14]([c:17]([C:20]([F:21])([F:22])[F:23])[n:18][c:19]2[Br:36])[CH2:15][CH2:16]1)=[O:24])[CH2:25][c:26]1[c:27]([F:34])[cH:28][c:29]([F:33])[c:30]([F:32])[cH:31]1)=[O:35]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-e66ed5d872074a85a6f946a7ece47b69
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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