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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1118332Generated: November 1, 2026

Tetrahydrofuran → 7-{2-[3-(2-Ethoxycarbonyl-ethyl)-benzo[b]thiophen-6-yloxy]-ethyl}-3,4-dihydro-2H-[1,8]naphthyridine-1-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/1118332

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTriphenylphosphineHCID 11776—
ReactantDiisopropyl diazene-1,2-dicarboxylateHCID 75555—
ReactantEthyl 3-(6-hydroxybenzo[B]thiophen-3-YL)propanoateHCID 11288155—
Reactanttert-Butyl 7-(2-hydroxyethyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxylateHCID 58230650—
Product7-{2-[3-(2-Ethoxycarbonyl-ethyl)-benzo[b]thiophen-6-yloxy]-ethyl}-3,4-dihydro-2H-[1,8]naphthyridine-1-carboxylic acid tert-butyl esterHCID 69548100—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-2236ee1356fc4efa9ffa9f94cc3d9762
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)