Water → 4-(2,2-Dimethyl-propylamino)-6-[3-(4-propyl-piperazin-1-yl)-propoxy]-quinazoline-2-carbonitrile
Reaction equation
[C:33](=[O:34])([O-:35])[O-:36].[CH3:1][C:2]([CH2:3][NH:4][c:5]1[n:6][c:7]([C:16]#[N:17])[n:8][c:9]2[cH:10][cH:11][c:12]([OH:15])[cH:13][c:14]12)([CH3:18])[CH3:19].[Cl:20][CH2:21][CH2:22][CH2:23][N:24]1[CH2:25][CH2:26][N:27]([CH2:30][CH2:31][CH3:32])[CH2:28][CH2:29]1.[Cs+:37].[Cs+:38].[O:40]=[CH:41][N:42]([CH3:43])[CH3:44].[OH2:39]>>[CH3:1][C:2]([CH2:3][NH:4][c:5]1[n:6][c:7]([C:16]#[N:17])[n:8][c:9]2[cH:10][cH:11][c:12]([O:15][CH2:21][CH2:22][CH2:23][N:24]3[CH2:25][CH2:26][N:27]([CH2:30][CH2:31][CH3:32])[CH2:28][CH2:29]3)[cH:13][c:14]12)([CH3:18])[CH3:19]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-257436b78db9437aaaff46aeadc27851
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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