Dichloromethane → 4-(Azetidin-3-yl)-2,2-dimethylmorpholine

HRID 1118444Notes

Reaction equation

HRID 1118444 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH:10]([N:12]2[CH2:13][C:14]([CH3:18])([CH3:19])[O:15][CH2:16][CH2:17]2)[CH2:11]1)([CH3:5])([CH3:6])[CH3:7].[Cl:27][CH2:28][Cl:29].[F:20][C:21]([F:22])([F:23])[C:24]([OH:25])=[O:26]>>[NH:8]1[CH2:9][CH:10]([N:12]2[CH2:13][C:14]([CH3:18])([CH3:19])[O:15][CH2:16][CH2:17]2)[CH2:11]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 596059313-(2,2-Dimethylmorpholin-4-yl)azetidine-1-carboxylic acid tert-butyl ester

Product 1

HCID 627847954-(Azetidin-3-yl)-2,2-dimethylmorpholine

Sources & evidence

ORD record
ord-2b85297d34ab4c92bf5628e004636edb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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