Tetrahydrofuran → 2-[1-(2-chlorophenyl)pyrazolo[5,4-d]pyrimidin-4-yl]oxy-3-(2-hydroxyethoxy)-N-(5-methyl-2-pyridinyl)propanamide
Reaction equation
[C:19]([Si:20]([c:21]1[cH:22][cH:23][cH:57][cH:58][cH:59]1)([O:24][CH2:25][CH2:26][O:27][CH2:28][CH:29]([C:30](=[O:31])[NH:32][c:33]1[n:34][cH:35][c:36]([CH3:39])[cH:37][cH:38]1)[O:40][c:41]1[c:42]2[c:43]([n:44][cH:45][n:46]1)[n:47](-[c:50]1[c:51]([Cl:56])[cH:52][cH:53][cH:54][cH:55]1)[n:48][cH:49]2)[c:60]1[cH:61][cH:62][cH:63][cH:64][cH:65]1)([CH3:66])([CH3:67])[CH3:68].[CH2:69]1[O:70][CH2:71][CH2:72][CH2:73]1.[CH3:2][CH2:3][CH2:4][CH2:5][N+:6]([CH2:7][CH2:8][CH2:9][CH3:10])([CH2:11][CH2:12][CH2:13][CH3:14])[CH2:15][CH2:16][CH2:17][CH3:18].[F-:1]>>[OH:24][CH2:25][CH2:26][O:27][CH2:28][CH:29]([C:30](=[O:31])[NH:32][c:33]1[n:34][cH:35][c:36]([CH3:39])[cH:37][cH:38]1)[O:40][c:41]1[c:42]2[c:43]([n:44][cH:45][n:46]1)[n:47](-[c:50]1[c:51]([Cl:56])[cH:52][cH:53][cH:54][cH:55]1)[n:48][cH:49]2Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-4c0d025f6bd14c62b1debfab8c16c54f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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