Pyrrolidine → Tert-butyl 6-[({2'-cyano-4'-[(methoxycarbonyl)methyl]-1,1'-biphenyl-4-yl}oxy)methyl]-2-hydroxy-3-(trifluoromethyl)benzoate
Reaction equation
[C:6]([O:7][C:8](=[O:9])[O:13][c:14]1[c:15]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[c:23]([CH2:31][O:32][c:33]2[cH:34][cH:35][c:36](-[c:39]3[c:40]([C:50]#[N:51])[cH:41][c:42]([CH2:45][C:46](=[O:47])[O:48][CH3:49])[cH:43][cH:44]3)[cH:37][cH:38]2)[cH:24][cH:25][c:26]1[C:27]([F:28])([F:29])[F:30])([CH3:10])([CH3:11])[CH3:12].[CH2:1]1[CH2:2][NH:3][CH2:4][CH2:5]1.[CH2:52]1[O:53][CH2:54][CH2:55][O:56][CH2:57]1>>[OH:13][c:14]1[c:15]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[c:23]([CH2:31][O:32][c:33]2[cH:34][cH:35][c:36](-[c:39]3[c:40]([C:50]#[N:51])[cH:41][c:42]([CH2:45][C:46](=[O:47])[O:48][CH3:49])[cH:43][cH:44]3)[cH:37][cH:38]2)[cH:24][cH:25][c:26]1[C:27]([F:28])([F:29])[F:30]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-6fd7ca0d2bab48a6a82947c03214d425
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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