Pyridine → Tert-butyl 4-(chlorocarbonyl)piperazine-1-carboxylate

HRID 1119748Notes

Reaction equation

HRID 1119748 reaction equation
[Cl:1][C:2]([Cl:3])([O:4][C:5](=[O:6])[O:7][C:8]([Cl:9])([Cl:10])[Cl:11])[Cl:12].[Cl:32][CH2:33][Cl:34].[N:13]1([C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[CH2:14][CH2:15][NH:16][CH2:17][CH2:18]1.[cH:26]1[cH:27][cH:28][n:29][cH:30][cH:31]1>>[Cl:1][C:2](=[O:4])[N:16]1[CH2:15][CH2:14][N:13]([C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[CH2:18][CH2:17]1

Participants

5

Reactant 4

HCID 1049PyridineHCID 6344DichloromethaneHCID 94429TriphosgeneHCID 143452tert-Butyl piperazine-1-carboxylate

Product 1

HCID 11334154Tert-butyl 4-(chlorocarbonyl)piperazine-1-carboxylate

Sources & evidence

ORD record
ord-dc45c867e91c40ebb802c28bbb4a7905
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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