Dichloromethane → 2'-(Bromomethyl)-4-fluoro-5-isopropyl-2-methoxy-4'-(trifluoromethyl)biphenyl-3-ol
Reaction equation
[C:20]([Br:21])([Br:22])([Br:23])[Br:24].[Cl:50][CH2:51][Cl:52].[F:25][c:26]1[c:27]([OH:49])[c:28]([O:47][CH3:48])[c:29](-[c:35]2[c:36]([CH2:45][OH:46])[cH:37][c:38]([C:41]([F:42])([F:43])[F:44])[cH:39][cH:40]2)[cH:30][c:31]1[CH:32]([CH3:33])[CH3:34].[c:1]1([P:2]([c:3]2[cH:4][cH:5][cH:6][cH:7][cH:8]2)[c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)[cH:15][cH:16][cH:17][cH:18][cH:19]1>>[CH2:20]([Br:24])[c:36]1[c:35](-[c:29]2[c:28]([O:47][CH3:48])[c:27]([OH:49])[c:26]([F:25])[c:31]([CH:32]([CH3:33])[CH3:34])[cH:30]2)[cH:40][cH:39][c:38]([C:41]([F:42])([F:43])[F:44])[cH:37]1Participants
5
Sources & evidence
- ORD record
- ord-fa72471b72254355905dc4f523b0e07f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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