Dimethylformamide → 4-[4-Butyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-ylmethoxymethyl]-2-fluoro-benzoic acid methyl ester
Reaction equation
[C:22](=[O:23])([O-:24])[O-:25].[CH2:1]([CH2:2][CH2:3][CH3:4])[c:5]1[n:6][c:7](-[c:12]2[cH:13][cH:14][c:15]([C:18]([F:19])([F:20])[F:21])[cH:16][cH:17]2)[s:8][c:9]1[CH2:10][OH:11].[CH3:28][O:29][C:30]([c:31]1[c:32]([F:39])[cH:33][c:34]([CH2:37][Br:38])[cH:35][cH:36]1)=[O:40].[Cs+:26].[Cs+:27].[O:41]=[CH:42][N:43]([CH3:44])[CH3:45]>>[CH2:1]([CH2:2][CH2:3][CH3:4])[c:5]1[n:6][c:7](-[c:12]2[cH:13][cH:14][c:15]([C:18]([F:19])([F:20])[F:21])[cH:16][cH:17]2)[s:8][c:9]1[CH2:10][O:11][CH2:37][c:34]1[cH:33][c:32]([F:39])[c:31]([C:30]([O:29][CH3:28])=[O:40])[cH:36][cH:35]1Participants
6
Sources & evidence
- ORD record
- ord-b63a24af4b34480492301f8fdfd5d547
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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