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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1120314Generated: November 1, 2026

Ammonium → tert-Butyl 4-hydroxy-4-(4-(trifluoromethoxy)phenyl)piperidine-1-carboxylate

https://huagongshe.com/reaction/1120314

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniumHCID 223—
ReactantChlorideHCID 312—
ReactantTetrahydrofuranHCID 8028—
Reactant1-Bromo-4-(trifluoromethoxy)benzeneHCID 521008—
Reactant4-Carbonyl piperidine-1-formic acid tert-butyl esterHCID 86685902—
ReactantButyllithiumHCID 178418339—
Producttert-Butyl 4-hydroxy-4-(4-(trifluoromethoxy)phenyl)piperidine-1-carboxylateHCID 68626953—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-396b577e815e48e0be77584c510e66c3
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)