Dichloromethane → N-[4-[(5,6,7,8-Tetrahydro-4H-thieno[3,2-b]azepin-4-yl)carbonyl]-3-chlorophenyl][1,1'-biphenyl]-2-carboxamide

HRID 1120347Notes

Reaction equation

HRID 1120347 reaction equation
[CH3:21][CH2:22][N:23]([CH2:24][CH3:25])[CH2:26][CH3:27].[Cl:1][c:2]1[c:3]([C:4](=[O:5])[N:6]2[c:7]3[c:8]([s:13][cH:14][cH:15]3)[CH2:9][CH2:10][CH2:11][CH2:12]2)[cH:16][cH:17][c:18]([NH2:20])[cH:19]1.[Cl:43][CH2:44][Cl:45].[c:28]1(-[c:37]2[cH:38][cH:39][cH:40][cH:41][cH:42]2)[c:29]([C:34](=[O:35])[Cl:36])[cH:30][cH:31][cH:32][cH:33]1>>[Cl:1][c:2]1[c:3]([C:4](=[O:5])[N:6]2[c:7]3[c:8]([s:13][cH:14][cH:15]3)[CH2:9][CH2:10][CH2:11][CH2:12]2)[cH:16][cH:17][c:18]([NH:20][C:34]([c:29]2[c:28](-[c:37]3[cH:38][cH:39][cH:40][cH:41][cH:42]3)[cH:33][cH:32][cH:31][cH:30]2)=[O:35])[cH:19]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 12563768[1,1'-Biphenyl]-2-carbonyl chlorideHCID 214671284-(2-Chloro-4-aminobenzoyl)-5,6,7,8-tetrahydro-4H-thieno[3,2-b]azepine

Product 1

HCID 21467141N-[4-[(5,6,7,8-Tetrahydro-4H-thieno[3,2-b]azepin-4-yl)carbonyl]-3-chlorophenyl][1,1'-biphenyl]-2-carboxamide

Sources & evidence

ORD record
ord-eef2a7fbb861442ba7290381afdb4803
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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