Acetic Acid → 8-Chloro-6,7-difluoro-1-(3,5-difluoro-6-isopropylaminopyridin-2-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
Reaction equation
[CH3:33][C:34](=[O:35])[OH:36].[Cl:2][c:3]1[c:4]([F:32])[c:5]([F:31])[cH:6][c:7]2[c:8](=[O:30])[c:9]([C:25](=[O:26])[O:27][CH2:28][CH3:29])[cH:10][n:11](-[c:13]3[n:14][c:15]([NH:21][CH:22]([CH3:23])[CH3:24])[c:16]([F:20])[cH:17][c:18]3[F:19])[c:12]12.[ClH:1]>>[Cl:2][c:3]1[c:4]([F:32])[c:5]([F:31])[cH:6][c:7]2[c:8](=[O:30])[c:9]([C:25](=[O:26])[OH:27])[cH:10][n:11](-[c:13]3[n:14][c:15]([NH:21][CH:22]([CH3:23])[CH3:24])[c:16]([F:20])[cH:17][c:18]3[F:19])[c:12]12Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-db7810e489fa45769309c1b543aad49b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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