Dichloromethane → 4-[3-(6-Cyclopropyl-pyridin-3-yl)-phenyl]-8-trifluoromethoxy-1,3-dihydro-benzo[b][1,4]diazepin-2-one
Reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:7][c:8]1[c:9]([NH:19][C:20]([CH2:21][C:22](=[O:5])[c:24]2[cH:25][c:26](-[c:30]3[cH:31][n:32][c:33]([CH:36]4[CH2:37][CH2:38]4)[cH:34][cH:35]3)[cH:27][cH:28][cH:29]2)=[O:39])[cH:10][c:11]([O:14][C:15]([F:16])([F:17])[F:18])[cH:12][cH:13]1)([CH3:6])([CH3:23])[CH3:40].[Cl:48][CH2:49][Cl:50].[F:41][C:42]([F:43])([F:44])[C:45]([OH:46])=[O:47]>>[N:7]1=[C:22]([c:24]2[cH:25][c:26](-[c:30]3[cH:31][n:32][c:33]([CH:36]4[CH2:37][CH2:38]4)[cH:34][cH:35]3)[cH:27][cH:28][cH:29]2)[CH2:21][C:20](=[O:39])[NH:19][c:9]2[c:8]1[cH:13][cH:12][c:11]([O:14][C:15]([F:16])([F:17])[F:18])[cH:10]2Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-03058cdc9bc142c5b47a7e35c6f3bee5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
Loading…