1-Butanol → N-[1-(3-cyano-4,6-dimethylpyridin-2-yl)azetidin-3-yl]-2-(3-fluorophenyl)pyrimidine-5-carboxamide
Reaction equation
[CH2:32]([OH:33])[CH2:34][CH2:35][CH3:36].[CH3:38][CH2:39][O:40][C:41](=[O:42])[CH3:43].[Cl:21][c:22]1[c:23]([C:24]#[N:25])[c:26]([CH3:31])[cH:27][c:28]([CH3:30])[n:29]1.[NH:1]1[CH2:2][CH:3]([NH:5][C:6](=[O:7])[c:8]2[cH:9][n:10][c:11](-[c:14]3[cH:15][c:16]([F:20])[cH:17][cH:18][cH:19]3)[n:12][cH:13]2)[CH2:4]1.[OH2:37]>>[N:1]1([c:22]2[c:23]([C:24]#[N:25])[c:26]([CH3:31])[cH:27][c:28]([CH3:30])[n:29]2)[CH2:2][CH:3]([NH:5][C:6](=[O:7])[c:8]2[cH:9][n:10][c:11](-[c:14]3[cH:15][c:16]([F:20])[cH:17][cH:18][cH:19]3)[n:12][cH:13]2)[CH2:4]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-a77a04f309b5432bb3c63e55fdcdfe01
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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