Dichloromethane → 4-Chloro-2-methylsulfanylpyrimidine-5-carboxylic acid (4-fluorophenyl)amide

HRID 1121251Notes

Reaction equation

[CH:21]([N:22]([CH2:23][CH3:24])[CH:25]([CH3:26])[CH3:27])([CH3:28])[CH3:29].[Cl:1][c:2]1[n:3][c:4]([S:11][CH3:12])[n:5][cH:6][c:7]1[C:8](=[O:9])[Cl:10].[Cl:30][CH2:31][Cl:32].[NH2:13][c:14]1[cH:15][cH:16][c:17]([F:18])[cH:19][cH:20]1>>[Cl:1][c:2]1[n:3][c:4]([S:11][CH3:12])[n:5][cH:6][c:7]1[C:8](=[O:9])[NH:13][c:14]1[cH:15][cH:16][c:17]([F:18])[cH:19][cH:20]1

Participants

Reactant 4

HCID 6344Dichloromethane

HCID 97314-Fluoroaniline

HCID 81531Diisopropylethylamine

HCID 189690784-Chloro-2-(methylsulfanyl)pyrimidine-5-carbonyl chloride

Product 1

HCID 188588054-Chloro-2-methylsulfanylpyrimidine-5-carboxylic acid (4-fluorophenyl)amide

Sources & evidence

ORD record: ord-656888d3db904da1816fea775e0dd8d6
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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