Dichloromethane → 3-Methyl-8-piperazin-1-yl-7-prop-2-enylpurine-2,6-dione

HRID 1121396Notes

Reaction equation

HRID 1121396 reaction equation
[C:8]([O:9][C:10](=[O:11])[N:15]1[CH2:16][CH2:17][N:18]([c:21]2[n:22][c:23]3[n:24]([CH3:35])[c:25](=[O:34])[nH:26][c:27](=[O:33])[c:28]3[n:29]2[CH2:30][CH:31]=[CH2:32])[CH2:19][CH2:20]1)([CH3:12])([CH3:13])[CH3:14].[CH2:36]([Cl:37])[Cl:38].[OH:1][C:2]([C:3]([F:4])([F:5])[F:6])=[O:7]>>[NH:15]1[CH2:16][CH2:17][N:18]([c:21]2[n:22][c:23]3[n:24]([CH3:35])[c:25](=[O:34])[nH:26][c:27](=[O:33])[c:28]3[n:29]2[CH2:30][CH:31]=[CH2:32])[CH2:19][CH2:20]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 235369544-(7-Allyl-3-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperazine-1-carboxylic acid tert-butyl ester

Product 1

HCID 6774233-Methyl-8-piperazin-1-yl-7-prop-2-enylpurine-2,6-dione

Sources & evidence

ORD record
ord-f81893a822004e7a8a1f5ed191c670ea
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

Loading…