Potassium Cation → 3-[7-[[4-(8-oxa-3-azabicyclo[3.2.1]octan-3-ylmethyl)phenyl]methoxy]-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione

HRID 1121626Notes

Reaction equation

HRID 1121626 reaction equation
[CH2:47]1[O:48][CH2:49][CH2:50][CH2:51]1.[CH3:41][C:42]([CH3:43])([O-:44])[CH3:45].[CH:1]12[CH2:2][N:3]([CH2:9][c:10]3[cH:11][cH:12][c:13]([CH2:14][O:15][c:16]4[c:17]5[c:21]([cH:22][cH:23][cH:24]4)[C:20](=[O:25])[N:19]([CH:26]([C:27]([O:29][C:28]([CH3:30])([CH3:31])[CH3:32])=[O:33])[CH2:34][CH2:35][C:36](=[O:37])[NH2:38])[CH2:18]5)[cH:39][cH:40]3)[CH2:4][CH:5]([CH2:6][CH2:7]1)[O:8]2.[K+:46]>>[CH:1]12[CH2:2][N:3]([CH2:9][c:10]3[cH:11][cH:12][c:13]([CH2:14][O:15][c:16]4[c:17]5[c:21]([cH:22][cH:23][cH:24]4)[C:20](=[O:25])[N:19]([CH:26]4[C:27](=[O:29])[NH:38][C:36](=[O:37])[CH2:35][CH2:34]4)[CH2:18]5)[cH:39][cH:40]3)[CH2:4][CH:5]([CH2:6][CH2:7]1)[O:8]2

Participants

5

Reactant 4

HCID 813Potassium CationHCID 8028TetrahydrofuranHCID 45749132-Methylpropan-2-olateHCID 67333694tert-butyl 5-amino-2-[7-[[4-(8-oxa-3-azabicyclo[3.2.1]octan-3-ylmethyl)phenyl]methoxy]-3-oxo-1H-isoindol-2-yl]-5-oxopentanoate

Product 1

HCID 583892653-[7-[[4-(8-oxa-3-azabicyclo[3.2.1]octan-3-ylmethyl)phenyl]methoxy]-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione

Sources & evidence

ORD record
ord-776f50c2abac45d08f55d1ed3d261d1e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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