Chloride → 1-[7-(2-chloro-acetyl)-3,4-dihydro-1H-isoquinolin-2-yl]-2,2,2-trifluoro-ethanone
Reaction equation
[Al+3:2].[Cl-:1].[Cl-:3].[Cl-:4].[Cl:27][CH2:28][Cl:29].[Cl:5][CH2:6][C:7](=[O:8])[Cl:9].[F:10][C:11]([C:12](=[O:13])[N:14]1[CH2:15][c:16]2[cH:17][cH:18][cH:19][cH:20][c:21]2[CH2:22][CH2:23]1)([F:24])[F:25].[OH2:26]>>[Cl:5][CH2:6][C:7](=[O:8])[c:18]1[cH:17][c:16]2[c:21]([cH:20][cH:19]1)[CH2:22][CH2:23][N:14]([C:12]([C:11]([F:10])([F:24])[F:25])=[O:13])[CH2:15]2Participants
7
Sources & evidence
- ORD record
- ord-e22919c025d345d197dcc9b0050e606a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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