N-methyl-2-pyrrolidone → 4-[3-(3,5-Dichlorophenyl)-1-methyl-2,4-dioxo-1,3-diazaspiro[4.4]nonan-9-yl]benzonitrile
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([CH:8]2[C:9]3([C:10](=[O:24])[N:11]([c:16]4[cH:17][c:18]([Cl:23])[cH:19][c:20]([Cl:22])[cH:21]4)[C:12](=[O:15])[N:13]3[CH3:14])[CH2:25][CH2:26][CH2:27]2)[cH:6][cH:7]1.[CH3:31][N:32]1[CH2:33][CH2:34][CH2:35][C:36]1=[O:37].[Cu:28][C:29]#[N:30]>>[c:2]1([C:29]#[N:30])[cH:3][cH:4][c:5]([CH:8]2[C:9]3([C:10](=[O:24])[N:11]([c:16]4[cH:17][c:18]([Cl:23])[cH:19][c:20]([Cl:22])[cH:21]4)[C:12](=[O:15])[N:13]3[CH3:14])[CH2:25][CH2:26][CH2:27]2)[cH:6][cH:7]1Participants
4
Sources & evidence
- ORD record
- ord-69f4212655dd47a8bd27c81c1ff80a7c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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