Hydrochloric Acid → 7-Benzyloxy-4-(4-chloro-2-fluorophenoxy)-6-methoxyquinazoline

HRID 1121706Notes

Reaction equation

HRID 1121706 reaction equation
[CH2:11]([c:12]1[cH:13][cH:14][cH:15][cH:16][cH:17]1)[O:18][c:19]1[c:20]([O:30][CH3:31])[cH:21][c:22]2[c:23]([Cl:29])[n:24][cH:25][n:26][c:27]2[cH:28]1.[Cl:1][c:2]1[cH:3][c:4]([F:9])[c:5]([OH:8])[cH:6][cH:7]1.[ClH:10].[cH:32]1[cH:33][cH:34][n:35][cH:36][cH:37]1>>[Cl:1][c:2]1[cH:3][c:4]([F:9])[c:5]([O:8][c:23]2[c:22]3[cH:21][c:20]([O:30][CH3:31])[c:19]([O:18][CH2:11][c:12]4[cH:13][cH:14][cH:15][cH:16][cH:17]4)[cH:28][c:27]3[n:26][cH:25][n:24]2)[cH:6][cH:7]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 1049PyridineHCID 1819754-Chloro-2-fluorophenolHCID 106619987-(Benzyloxy)-4-chloro-6-methoxyquinazoline

Product 1

HCID 218748257-Benzyloxy-4-(4-chloro-2-fluorophenoxy)-6-methoxyquinazoline

Sources & evidence

ORD record
ord-96c85a0bd86348a197ca4ef2cd88b4cd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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