Hydrochloric Acid → 3-(aminomethyl)-5-fluoro-2-N-[1-(4-fluorophenyl)ethyl]-6-N-(3-propan-2-yloxy-1H-pyrazol-5-yl)pyridine-2,6-diamine

HRID 1121873Notes

Reaction equation

HRID 1121873 reaction equation
[CH3:31][OH:32].[ClH:30].[F:1][c:2]1[c:3]([NH:20][c:21]2[n:22][nH:23][c:24]([O:26][CH:27]([CH3:28])[CH3:29])[cH:25]2)[n:4][c:5]([NH:10][CH:11]([CH3:12])[c:13]2[cH:14][cH:15][c:16]([F:19])[cH:17][cH:18]2)[c:6]([C:7]#[N:8])[cH:9]1>>[F:1][c:2]1[c:3]([NH:20][c:21]2[n:22][nH:23][c:24]([O:26][CH:27]([CH3:28])[CH3:29])[cH:25]2)[n:4][c:5]([NH:10][CH:11]([CH3:12])[c:13]2[cH:14][cH:15][c:16]([F:19])[cH:17][cH:18]2)[c:6]([CH2:7][NH2:8])[cH:9]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 887MethanolHCID 178458619HCID 178458619, compound

Product 1

HCID 1784586203-(aminomethyl)-5-fluoro-2-N-[1-(4-fluorophenyl)ethyl]-6-N-(3-propan-2-yloxy-1H-pyrazol-5-yl)pyridine-2,6-diamine

Sources & evidence

ORD record
ord-48ce3b7debb64d97ba9db272b486f233
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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