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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1121918Generated: October 31, 2026

Dimethylformamide → {2-[6-Methoxy-7-methyl-3-oxo-4-(2-trimethylsilany-ethoxy)-1,3-dihydro-isobenzofuran-5-yl]-ethoxymethyl}-phosphonic Acid Diisopropyl Ester

https://huagongshe.com/reaction/1121918

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantLithium ionHCID 28486—
ReactantDiisopropyl bromomethylphosphonateHCID 4366885—
Reactant2-Methylpropan-2-olateHCID 4574913—
Reactant6-(2-Hydroxy-ethyl)-5-methoxy-4-methyl-7-(2-trimethylsilanyl-ethoxy)-3H-isobenzofuran-1-oneHCID 57459851—
Product{2-[6-Methoxy-7-methyl-3-oxo-4-(2-trimethylsilany-ethoxy)-1,3-dihydro-isobenzofuran-5-yl]-ethoxymethyl}-phosphonic Acid Diisopropyl EsterHCID 57478687—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-d010f779adf24a4194bc8584ef8340dc
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)