Dimethyl Sulfoxide → 2-(4-(1,3-Dioxan-2-yl)-2-fluorophenyl)-5-(1-(3,3-difluoro-cyclobutyl)cyclopropyl)thiazolo[5,4-b]pyridine
Reaction equation
[CH2:43]1[O:44][CH2:45][CH2:46][CH2:47]1.[CH3:32][S+:33]([CH3:34])([CH3:35])=[O:36].[CH3:37][C:38]([O-:39])([CH3:40])[CH3:41].[CH3:48][S:49]([CH3:50])=[O:51].[I-:31].[K+:42].[O:1]1[CH:2]([c:7]2[cH:8][c:9]([F:30])[c:10](-[c:13]3[s:14][c:15]4[n:16][c:17]([C:22](=[CH2:23])[CH:24]5[CH2:25][C:26]([F:28])([F:29])[CH2:27]5)[cH:18][cH:19][c:20]4[n:21]3)[cH:11][cH:12]2)[O:3][CH2:4][CH2:5][CH2:6]1>>[O:1]1[CH:2]([c:7]2[cH:8][c:9]([F:30])[c:10](-[c:13]3[s:14][c:15]4[n:16][c:17]([C:22]5([CH:24]6[CH2:25][C:26]([F:28])([F:29])[CH2:27]6)[CH2:23][CH2:32]5)[cH:18][cH:19][c:20]4[n:21]3)[cH:11][cH:12]2)[O:3][CH2:4][CH2:5][CH2:6]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-8a18baff195a4bcc8530a310230c2069
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
Loading…