Piperazine → 5-Amino-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid
Reaction equation
[CH2:22]1[CH2:23][NH:24][CH2:25][CH2:26][NH:27]1.[CH3:28][C:29]#[N:30].[NH2:1][c:2]1[c:3]2[c:4](=[O:21])[c:5]([C:18](=[O:19])[OH:20])[cH:6][n:7]([CH:15]3[CH2:16][CH2:17]3)[c:8]2[c:9]([Cl:14])[c:10]([F:13])[c:11]1[F:12]>>[NH2:1][c:2]1[c:3]2[c:4](=[O:21])[c:5]([C:18](=[O:19])[OH:20])[cH:6][n:7]([CH:15]3[CH2:16][CH2:17]3)[c:8]2[c:9]([Cl:14])[c:10]([N:24]2[CH2:23][CH2:22][NH:27][CH2:26][CH2:25]2)[c:11]1[F:12]Participants
4
Sources & evidence
- ORD record
- ord-b2ad2321b8244a5d8398b2a8cb66321c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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