Tetrahydrofuran → Tert-butyl 3-hydroxy-3-[2-(phenoxymethyl)prop-2-enyl]-2-phenylpiperidine-1-carboxylate
Reaction equation
[C:14]([CH3:15])([CH3:16])([CH3:17])[O:18][C:19](=[O:20])[N:21]1[CH:22]([c:28]2[cH:29][cH:30][cH:31][cH:32][cH:33]2)[C:23](=[O:27])[CH2:24][CH2:25][CH2:26]1.[Cl:1][Mg:2][CH2:3][C:4](=[CH2:5])[CH2:6][O:7][c:8]1[cH:9][cH:10][cH:11][cH:12][cH:13]1.[O:34]1[CH2:35][CH2:36][CH2:37][CH2:38]1>>[CH2:3]([C:4](=[CH2:5])[CH2:6][O:7][c:8]1[cH:9][cH:10][cH:11][cH:12][cH:13]1)[C:23]1([OH:27])[CH:22]([c:28]2[cH:29][cH:30][cH:31][cH:32][cH:33]2)[N:21]([C:19]([O:18][C:14]([CH3:15])([CH3:16])[CH3:17])=[O:20])[CH2:26][CH2:25][CH2:24]1Participants
4
Sources & evidence
- ORD record
- ord-7b8e7691b68c441784c5bb3a56526ee0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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