Tetrahydrofuran → Tert-butyl 3-(2,3-difluoro-6-methylbenzoyl)piperidine-1-carboxylate
Reaction equation
[CH2:29]1[O:30][CH2:31][CH2:32][CH2:33]1.[F:1][c:2]1[c:3]([C:4](=[O:5])[CH:6]2[CH2:7][N:8]([C:12](=[O:13])[O:14][C:15]([CH3:16])([CH3:17])[CH3:18])[CH2:9][CH2:10][CH2:11]2)[c:19]([CH3:28])[cH:20][c:21]([Si:24]([CH3:25])([CH3:26])[CH3:27])[c:22]1[F:23]>>[F:1][c:2]1[c:3]([C:4](=[O:5])[CH:6]2[CH2:7][N:8]([C:12](=[O:13])[O:14][C:15]([CH3:16])([CH3:17])[CH3:18])[CH2:9][CH2:10][CH2:11]2)[c:19]([CH3:28])[cH:20][cH:21][c:22]1[F:23]Participants
3
Sources & evidence
- ORD record
- ord-659de4982440479f91005f46eefdad9a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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