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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1122348Generated: October 31, 2026

Methanol → N-[[4-thiophen-2-ylsulfonyl-1-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]piperazin-2-yl]methyl]propane-2-sulfonamide

https://huagongshe.com/reaction/1122348

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
ReactantPyridineHCID 1049—
ReactantDichloromethaneHCID 6344—
ReactantDiisopropylethylamineHCID 81531—
Reactant2-Propanesulfonyl chlorideHCID 82408—
Reactant2-[4-[2-(Aminomethyl)-4-thiophen-2-ylsulfonylpiperazin-1-yl]phenyl]-1,1,1-trifluoropropan-2-olHCID 77148386—
ProductN-[[4-thiophen-2-ylsulfonyl-1-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]piperazin-2-yl]methyl]propane-2-sulfonamideHCID 76462500—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-9399e1bd7a9d4ea2bc29e8de65c369ec
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)