Methanol → N-[[4-thiophen-2-ylsulfonyl-1-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]piperazin-2-yl]methyl]propane-2-sulfonamide
Reaction equation
[CH3:55][OH:56].[CH:36]([CH3:37])([CH3:38])[S:39](=[O:40])(=[O:41])[Cl:42].[CH:43]([N:44]([CH2:45][CH3:46])[CH:47]([CH3:48])[CH3:49])([CH3:50])[CH3:51].[Cl:52][CH2:53][Cl:54].[NH2:1][CH2:2][CH:3]1[N:4]([c:17]2[cH:18][cH:19][c:20]([C:23]([C:24]([F:25])([F:26])[F:27])([CH3:28])[OH:29])[cH:21][cH:22]2)[CH2:5][CH2:6][N:7]([S:9](=[O:10])(=[O:11])[c:12]2[s:13][cH:14][cH:15][cH:16]2)[CH2:8]1.[cH:30]1[cH:31][cH:32][n:33][cH:34][cH:35]1>>[NH:1]([CH2:2][CH:3]1[N:4]([c:17]2[cH:18][cH:19][c:20]([C:23]([C:24]([F:25])([F:26])[F:27])([CH3:28])[OH:29])[cH:21][cH:22]2)[CH2:5][CH2:6][N:7]([S:9](=[O:10])(=[O:11])[c:12]2[s:13][cH:14][cH:15][cH:16]2)[CH2:8]1)[S:39]([CH:36]([CH3:37])[CH3:38])(=[O:40])=[O:41]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-9399e1bd7a9d4ea2bc29e8de65c369ec
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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