Dimethylformamide → 3-{4-[5-(2-Amino-pyrimidin-5-yl)-1-tert-butyl-1H-benzoimidazol-2-yl]-3-[1,2,4]triazol-1-yl-phenoxy}-2,2-dimethyl-propionic acid ethyl ester
Reaction equation
[C:33](=[O:34])([O-:35])[O-:36].[Cl:39][CH2:40][C:41]([C:42](=[O:43])[O:44][CH2:45][CH3:46])([CH3:47])[CH3:48].[Cs+:37].[Cs+:38].[NH2:1][c:2]1[n:3][cH:4][c:5](-[c:8]2[cH:9][c:10]3[c:11]([n:12]([C:27]([CH3:28])([CH3:29])[CH3:30])[c:13](-[c:15]4[c:16](-[n:22]5[n:23][cH:24][n:25][cH:26]5)[cH:17][c:18]([OH:21])[cH:19][cH:20]4)[n:14]3)[cH:31][cH:32]2)[cH:6][n:7]1.[O:49]=[CH:50][N:51]([CH3:52])[CH3:53]>>[NH2:1][c:2]1[n:3][cH:4][c:5](-[c:8]2[cH:9][c:10]3[c:11]([n:12]([C:27]([CH3:28])([CH3:29])[CH3:30])[c:13](-[c:15]4[c:16](-[n:22]5[n:23][cH:24][n:25][cH:26]5)[cH:17][c:18]([O:21][CH2:40][C:41]([C:42](=[O:43])[O:44][CH2:45][CH3:46])([CH3:47])[CH3:48])[cH:19][cH:20]4)[n:14]3)[cH:31][cH:32]2)[cH:6][n:7]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-e7bdb1644ece4507983038032ac02f12
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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