Acetic Acid → 4-(5-Fluoro-2-methoxyphenyl)-1-(2-methoxyquinolin-5-ylamino)-4-methyl-2-(trifluoromethyl)pentan-2-ol

HRID 1123129Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1123129
[C:35]([O:36][BH-:37]([O:38][C:39](=[O:40])[CH3:41])[O:42][C:43](=[O:44])[CH3:45])(=[O:46])[CH3:47].[CH3:49][c:50]1[cH:51][cH:52][cH:53][cH:54][cH:55]1.[CH3:56][C:57](=[O:58])[OH:59].[F:1][c:2]1[cH:3][cH:4][c:5]([O:20][CH3:21])[c:6]([C:8]([CH2:9][C:10]([CH:11]=[O:12])([C:13]([F:14])([F:15])[F:16])[OH:17])([CH3:18])[CH3:19])[cH:7]1.[NH2:22][c:23]1[c:24]2[cH:25][cH:26][c:27]([O:33][CH3:34])[n:28][c:29]2[cH:30][cH:31][cH:32]1.[Na+:48]>>[F:1][c:2]1[cH:3][cH:4][c:5]([O:20][CH3:21])[c:6]([C:8]([CH2:9][C:10]([CH2:11][NH:22][c:23]2[c:24]3[cH:25][cH:26][c:27]([O:33][CH3:34])[n:28][c:29]3[cH:30][cH:31][cH:32]2)([C:13]([F:14])([F:15])[F:16])[OH:17])([CH3:18])[CH3:19])[cH:7]1

Komponenten

7

Edukt 6

HCID 176Acetic AcidHCID 923Sodium ionHCID 1140TolueneHCID 2724942TriacetoxyborohydrideHCID 115731224-(5-Fluoro-2-methoxy-phenyl)-2-hydroxy-4-methyl-2-(trifluoromethyl)pentanalHCID 122830362-Methoxyquinolin-5-amine

Produkt 1

HCID 219488414-(5-Fluoro-2-methoxyphenyl)-1-(2-methoxyquinolin-5-ylamino)-4-methyl-2-(trifluoromethyl)pentan-2-ol

Quellen und Nachweise

ORD-Eintrag
ord-f19b4394305d429f97bb42d56e17ddb1
Quelldatensatz
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

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