2-Methoxyethylamine → N-(3-chloro-2-fluorophenyl)-7-methoxy-6-{[(2-methoxyethyl)amino]methyl}quinazolin-4-amine

HRID 1123338Notes

Reaction equation

HRID 1123338 reaction equation
[Cl:1][c:2]1[c:3]([F:23])[c:4]([NH:5][c:6]2[n:7][cH:8][n:9][c:10]3[cH:11][c:12]([O:18][CH3:19])[c:13]([CH:16]=[O:17])[cH:14][c:15]23)[cH:20][cH:21][cH:22]1.[NH2:24][CH2:25][CH2:26][O:27][CH3:28]>>[Cl:1][c:2]1[c:3]([F:23])[c:4]([NH:5][c:6]2[n:7][cH:8][n:9][c:10]3[cH:11][c:12]([O:18][CH3:19])[c:13]([CH2:16][NH:24][CH2:25][CH2:26][O:27][CH3:28])[cH:14][c:15]23)[cH:20][cH:21][cH:22]1

Participants

3

Reactant 2

HCID 80182-MethoxyethylamineHCID 115734924-[(3-Chloro-2-fluorophenyl)amino]-7-methoxyquinazoline-6-carbaldehyde

Product 1

HCID 69047438N-(3-chloro-2-fluorophenyl)-7-methoxy-6-{[(2-methoxyethyl)amino]methyl}quinazolin-4-amine

Sources & evidence

ORD record
ord-c461e74d87fe47948390d0c1c57aa53a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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