Water → Methyl 2-{3-[2-(trifluoromethyl)phenoxy]pyrrolidin-1-yl}-1,3-thiazole-5-carboxylate
Reaction equation
[Br:1][c:2]1[s:3][c:4]([C:7](=[O:8])[O:9][CH3:10])[cH:5][n:6]1.[CH2:27]1[CH2:28][CH2:29][C:30]2=[N:35][CH2:34][CH2:33][CH2:32][N:31]2[CH2:36][CH2:37]1.[F:11][C:12]([c:13]1[c:14]([O:15][CH:16]2[CH2:17][NH:18][CH2:19][CH2:20]2)[cH:21][cH:22][cH:23][cH:24]1)([F:25])[F:26].[O:38]1[CH2:39][CH2:40][O:41][CH2:42][CH2:43]1.[OH2:44]>>[c:2]1([N:18]2[CH2:17][CH:16]([O:15][c:14]3[c:13]([C:12]([F:11])([F:25])[F:26])[cH:24][cH:23][cH:22][cH:21]3)[CH2:20][CH2:19]2)[s:3][c:4]([C:7](=[O:8])[O:9][CH3:10])[cH:5][n:6]1Participants
6
Sources & evidence
- ORD record
- ord-f7d8a682912f41af8369651186b1c7af
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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