Potassium Cation → 3-{2-(Benzoylaminomethyl)-4-[3-(biphenyl-4-yloxy)propoxy]phenyl}propionic acid tert-butyl ester

HRID 1123407Notes

Reaction equation

HRID 1123407 reaction equation
[Br:1][CH2:2][CH2:3][CH2:4][O:5][c:6]1[cH:7][cH:8][c:9](-[c:12]2[cH:13][cH:14][cH:15][cH:16][cH:17]2)[cH:10][cH:11]1.[C:18]([CH3:19])([CH3:20])([CH3:21])[O:22][C:23]([CH2:24][CH2:25][c:26]1[c:27]([CH2:33][NH:34][C:35]([c:36]2[cH:37][cH:38][cH:39][cH:40][cH:41]2)=[O:42])[cH:28][c:29]([OH:32])[cH:30][cH:31]1)=[O:43].[K+:44].[K+:45].[O-:46][C:47]([O-:48])=[O:49].[O:50]=[CH:51][N:52]([CH3:53])[CH3:54].[OH2:55]>>[CH2:2]([CH2:3][CH2:4][O:5][c:6]1[cH:7][cH:8][c:9](-[c:12]2[cH:13][cH:14][cH:15][cH:16][cH:17]2)[cH:10][cH:11]1)[O:32][c:29]1[cH:28][c:27]([CH2:33][NH:34][C:35]([c:36]2[cH:37][cH:38][cH:39][cH:40][cH:41]2)=[O:42])[c:26]([CH2:25][CH2:24][C:23]([O:22][C:18]([CH3:19])([CH3:20])[CH3:21])=[O:43])[cH:31][cH:30]1

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 962WaterHCID 6228DimethylformamideHCID 19660Carbonate IonHCID 152334631,1'-Biphenyl, 4-(3-bromopropoxy)-HCID 589795203-[2-(Benzoylamino-methyl)4-hydroxy-phenyl]propionic acid tert-butyl ester

Product 1

HCID 692320193-{2-(Benzoylaminomethyl)-4-[3-(biphenyl-4-yloxy)propoxy]phenyl}propionic acid tert-butyl ester

Sources & evidence

ORD record
ord-10b8844d87b744e6bbe99d8948456d94
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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