Dichloromethane → 2-[3-oxo-1-(toluene-4-sulfonyl)-1,2,3,4-tetrahydro-pyrazin-2-yl]-N-[2-(4-piperidin-1-ylmethyl-phenyl)-ethyl]-acetamide

HRID 1123506Notes

Reaction equation

HRID 1123506 reaction equation
[CH2:32]1[CH2:33][CH2:34][NH:35][CH2:36][CH2:37]1.[Cl:1][CH2:2][c:3]1[cH:4][cH:5][c:6]([CH2:9][CH2:10][NH:11][C:12]([CH2:13][CH:14]2[N:15]([S:21](=[O:22])(=[O:23])[c:24]3[cH:25][cH:26][c:27]([CH3:30])[cH:28][cH:29]3)[CH:16]=[CH:17][NH:18][C:19]2=[O:20])=[O:31])[cH:7][cH:8]1.[Cl:38][CH2:39][Cl:40]>>[CH2:2]([c:3]1[cH:4][cH:5][c:6]([CH2:9][CH2:10][NH:11][C:12]([CH2:13][CH:14]2[N:15]([S:21](=[O:22])(=[O:23])[c:24]3[cH:25][cH:26][c:27]([CH3:30])[cH:28][cH:29]3)[CH:16]=[CH:17][NH:18][C:19]2=[O:20])=[O:31])[cH:7][cH:8]1)[N:35]1[CH2:34][CH2:33][CH2:32][CH2:37][CH2:36]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 8082PiperidineHCID 68682701N-[2-(4-chloromethyl-phenyl)-ethyl]-2-[3-oxo-1-(toluene-4-sulfonyl)-1,2,3,4-tetrahydro-pyrazin-2-yl]-acetamide

Product 1

HCID 686782362-[3-oxo-1-(toluene-4-sulfonyl)-1,2,3,4-tetrahydro-pyrazin-2-yl]-N-[2-(4-piperidin-1-ylmethyl-phenyl)-ethyl]-acetamide

Sources & evidence

ORD record
ord-9efaafbb6562414397aafb248a5ab09c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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