Tetrahydrofuran → Tert-butyl 3-benzoylpyrrolidine-1-carboxylate

HRID 1123611Notes

Reaction equation

HRID 1123611 reaction equation
[Br:24][Mg:25][c:26]1[cH:27][cH:28][cH:29][cH:30][cH:31]1.[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([C:13]([NH:14][CH2:15][O:16][CH3:17])=[O:18])[CH2:11][CH2:12]1.[CH2:19]1[O:20][CH2:21][CH2:22][CH2:23]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([C:13](=[O:18])[c:26]2[cH:27][cH:28][cH:29][cH:30][cH:31]2)[CH2:11][CH2:12]1

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 666736983-(Methoxymethylcarbamoyl)pyrrolidine-1-carboxylic acid t-butyl esterHCID 178418255HCID 178418255, compound

Product 1

HCID 57419606Tert-butyl 3-benzoylpyrrolidine-1-carboxylate

Sources & evidence

ORD record
ord-10c70ff635334628b859f0dd8258698c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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