Diethyl Ether → Quinuclidin-4-ylmethanamine

HRID 1124132Notes

Reaction equation

HRID 1124132 reaction equation
[Al+3:12].[C:1](#[N:2])[C:3]12[CH2:4][CH2:5][N:6]([CH2:7][CH2:8]1)[CH2:9][CH2:10]2.[CH3:17][CH2:18][O:19][CH2:20][CH3:21].[H-:11].[H-:14].[H-:15].[H-:16].[Li+:13]>>[CH2:1]([NH2:2])[C:3]12[CH2:4][CH2:5][N:6]([CH2:7][CH2:8]1)[CH2:9][CH2:10]2

Participants

6

Reactant 5

HCID 3283Diethyl EtherHCID 28486Lithium ionHCID 104727Aluminum CationHCID 1412921-Azabicyclo[2.2.2]octane-4-carbonitrileHCID 166653Hydride4×

Product 1

HCID 22056669Quinuclidin-4-ylmethanamine

Sources & evidence

ORD record
ord-29981cde6f344852ac7ceb64af590d6c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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