Tetrahydrofuran → 4-Amino-N-[2-(1-azabicyclo[3.3.0]octan-5-yl)ethyl]-5-chloro-2,3-dihydrobenzo[b]furan-7-carboxamide
Reaction equation
[NH2:15][CH2:16][CH2:17][C:18]12[CH2:19][CH2:20][CH2:21][N:22]1[CH2:23][CH2:24][CH2:25]2.[NH2:1][c:2]1[c:3]([Cl:14])[cH:4][c:5]([C:11](=[O:12])[OH:13])[c:6]2[c:10]1[CH2:9][CH2:8][O:7]2.[O:26]1[CH2:27][CH2:28][CH2:29][CH2:30]1>>[NH2:1][c:2]1[c:3]([Cl:14])[cH:4][c:5]([C:11](=[O:13])[NH:15][CH2:16][CH2:17][C:18]23[CH2:19][CH2:20][CH2:21][N:22]2[CH2:23][CH2:24][CH2:25]3)[c:6]2[c:10]1[CH2:9][CH2:8][O:7]2Participants
4
Sources & evidence
- ORD record
- ord-5225d95be9674b80b004831ed6c3b061
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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