Hydrochloric Acid → 1-(4-Fluoro-3-methoxyphenyl)-4-(2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl)piperazine

HRID 1124279Notes

Reaction equation

HRID 1124279 reaction equation
[Br:22][c:23]1[cH:24][c:25]([O:30][CH3:31])[c:26]([F:29])[cH:27][cH:28]1.[CH3:2][C:3]1([CH3:21])[O:4][c:5]2[c:6]([c:8]([CH3:20])[c:9]([N:14]3[CH2:15][CH2:16][NH:17][CH2:18][CH2:19]3)[c:10]([CH3:13])[c:11]2[CH3:12])[CH2:7]1.[ClH:1]>>[CH3:2][C:3]1([CH3:21])[O:4][c:5]2[c:6]([c:8]([CH3:20])[c:9]([N:14]3[CH2:15][CH2:16][N:17]([c:23]4[cH:24][c:25]([O:30][CH3:31])[c:26]([F:29])[cH:27][cH:28]4)[CH2:18][CH2:19]3)[c:10]([CH3:13])[c:11]2[CH3:12])[CH2:7]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 136049094-Bromo-1-fluoro-2-methoxybenzeneHCID 667597311-(2,2,4,6,7-Pentamethyl-2,3-dihydro-1-benzofuran-5-yl)piperazine

Product 1

HCID 594850061-(4-Fluoro-3-methoxyphenyl)-4-(2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl)piperazine

Sources & evidence

ORD record
ord-6d19faae0f4e45cb8df7307e91dc978a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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