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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1124475Generated: October 30, 2026

Chloride → 8-(2-Chloro-benzenesulfonyl)-2-[2-(3-trifluoromethyl-phenyl)-ethyl]-2,8-diaza-spiro[4.5]decan-1-one

https://huagongshe.com/reaction/1124475

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChlorideHCID 312—
ReactantTolueneHCID 1140—
ReactantPhenethylamine, m-trifluoromethyl-HCID 104223—
ReactantDimethylalumanyliumHCID 16685399—
Reactant1-(2-Chloro-benzenesulfonyl)-4-(2-methoxy-ethyl)-piperidine-4-carboxylic acid ethyl esterHCID 66787676—
Product8-(2-Chloro-benzenesulfonyl)-2-[2-(3-trifluoromethyl-phenyl)-ethyl]-2,8-diaza-spiro[4.5]decan-1-oneHCID 59578039—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-fd68c58d3993442aba9f89e4493b0154
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)