Chloride → 8-(2-Chloro-benzenesulfonyl)-2-[2-(3-trifluoromethyl-phenyl)-ethyl]-2,8-diaza-spiro[4.5]decan-1-one
Reaction equation
[CH2:1]([O:2][C:4](=[O:5])[C:6]1([CH2:22][CH2:23][O:3][CH3:24])[CH2:7][CH2:8][N:9]([S:12](=[O:13])(=[O:14])[c:15]2[c:16]([Cl:21])[cH:17][cH:18][cH:19][cH:20]2)[CH2:10][CH2:11]1)[CH3:25].[CH3:27][Al+:28][CH3:29].[CH3:43][c:44]1[cH:45][cH:46][cH:47][cH:48][cH:49]1.[Cl-:26].[F:30][C:31]([c:32]1[cH:33][c:34]([CH2:38][CH2:39][NH2:40])[cH:35][cH:36][cH:37]1)([F:41])[F:42]>>[C:4]1(=[O:5])[C:6]2([CH2:7][CH2:8][N:9]([S:12](=[O:13])(=[O:14])[c:15]3[c:16]([Cl:21])[cH:17][cH:18][cH:19][cH:20]3)[CH2:10][CH2:11]2)[CH2:22][CH2:23][N:40]1[CH2:39][CH2:38][c:34]1[cH:33][c:32]([C:31]([F:30])([F:41])[F:42])[cH:37][cH:36][cH:35]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-fd68c58d3993442aba9f89e4493b0154
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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