Hydroxide → 5-Cyclobutyl-1,3-thiazol-2-amine

HRID 112463Notes

Reaction equation

HRID 112463 reaction equation
[NH2:1][c:2]1[s:3][c:4]([C:7]2([OH:11])[CH2:8][CH2:9][CH2:10]2)[cH:5][n:6]1.[OH-:19].[OH-:21].[OH:12][C:13]([C:14]([F:15])([F:16])[F:17])=[O:18].[Pd+2:20]>>[NH2:1][c:2]1[s:3][c:4]([CH:7]2[CH2:8][CH2:9][CH2:10]2)[cH:5][n:6]1

Participants

5

Reactant 4

HCID 961Hydroxide2×HCID 6422Trifluoroacetic acidHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 227313761-(2-Amino-1,3-thiazol-5-yl)cyclobutan-1-ol

Product 1

HCID 129914235-Cyclobutyl-1,3-thiazol-2-amine

Sources & evidence

ORD record
ord-1722e9600c474019b6457acb10b1bf1a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

Loading…