Bromide ion → 1-(2,2-Diphenylethyl)-4-methyl-4-piperidinol

HRID 1124669Notes

Reaction equation

HRID 1124669 reaction equation
[Br-:22].[CH3:23][Mg+:24].[O:25]1[CH2:26][CH2:27][CH2:28][CH2:29]1.[c:1]1([CH:7]([CH2:8][N:9]2[CH2:10][CH2:11][C:12](=[O:15])[CH2:13][CH2:14]2)[c:16]2[cH:17][cH:18][cH:19][cH:20][cH:21]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([CH:7]([CH2:8][N:9]2[CH2:10][CH2:11][C:12]([OH:15])([CH3:23])[CH2:13][CH2:14]2)[c:16]2[cH:17][cH:18][cH:19][cH:20][cH:21]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

5

Reactant 4

HCID 259Bromide ionHCID 8028TetrahydrofuranHCID 125156351-(2,2-Diphenylethyl)piperidin-4-oneHCID 178477777HCID 178477777, compound

Product 1

HCID 203750531-(2,2-Diphenylethyl)-4-methyl-4-piperidinol

Sources & evidence

ORD record
ord-238caa9198914b09be782f8722ee7846
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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