Bicarbonate Ion → 6-(7-(3-Chloropyridin-2-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-ylamino)-3,3-dimethylindolin-2-one
Reaction equation
[CH3:32][C:33]#[N:34].[CH3:40][CH2:41][O:42][C:43]([CH3:44])=[O:45].[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][n:7]1)[CH2:8][N:9]([c:12]1[n:13][cH:14][cH:15][cH:16][c:17]1[Cl:18])[CH2:10][CH2:11]2.[NH2:19][c:20]1[cH:21][cH:22][c:23]2[c:27]([cH:28]1)[NH:26][C:25](=[O:29])[C:24]2([CH3:30])[CH3:31].[Na+:39].[O-:35][C:36]([OH:37])=[O:38]>>[c:2]1([NH:19][c:20]2[cH:21][cH:22][c:23]3[c:27]([cH:28]2)[NH:26][C:25](=[O:29])[C:24]3([CH3:30])[CH3:31])[c:3]2[c:4]([n:5][cH:6][n:7]1)[CH2:8][N:9]([c:12]1[n:13][cH:14][cH:15][cH:16][c:17]1[Cl:18])[CH2:10][CH2:11]2Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-17a9a4ef739e4b979862121731dd8ba7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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