Dichloromethane → 4-(4-Bromo-7-methoxybenzofuran-2-ylmethoxy)-piperidine

HRID 1125240Notes

Reaction equation

HRID 1125240 reaction equation
[C:8]([O:9][C:10](=[O:11])[N:15]1[CH2:16][CH2:17][CH:18]([O:21][CH2:22][c:23]2[o:24][c:25]3[c:26]([cH:27]2)[c:28]([Br:34])[cH:29][cH:30][c:31]3[O:32][CH3:33])[CH2:19][CH2:20]1)([CH3:12])([CH3:13])[CH3:14].[Cl:35][CH2:36][Cl:37].[OH:1][C:2]([C:3]([F:4])([F:5])[F:6])=[O:7]>>[NH:15]1[CH2:16][CH2:17][CH:18]([O:21][CH2:22][c:23]2[o:24][c:25]3[c:26]([cH:27]2)[c:28]([Br:34])[cH:29][cH:30][c:31]3[O:32][CH3:33])[CH2:19][CH2:20]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 540770204-(4-Bromo-7-methoxybenzofuran-2-ylmethoxy)-piperidine-1-carboxylic Acid tert-butyl Ester

Product 1

HCID 187848694-(4-Bromo-7-methoxybenzofuran-2-ylmethoxy)-piperidine

Sources & evidence

ORD record
ord-be0428ef32284d738336e812e6892a41
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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